First, throw a Honey Jellybean at the Blob for him to eat. While he is transforming, throw a Ketchup Jellybean at the blob, and if done correctly, the Blob will transform into a Brick. What purpose this serves is beyond me, but it is a fun ''hidden secret'' to test out.
First, you will have to collect all of the hidden treasure in the lower areas (near the sewers and subway station) of the game. Once all of the treasure has been collected (there is a little bar on the playing screen showing how many treasures have been collected), head back to the beginning of the level and go to the far east (right) of the level to find the Vitamin Shop, which was once closed, is now open and you will receive a whole bunch of Extra Vitamins.
In this glitch, you need to give the Blob a Root Beer jellybean so he can take you to the grasslands. Then give the Blob a Punch jellybean so he can turn into a hole. then press whistle to turn him back. While he is turning back, go back into the whole while he is still a whole. You should be still be deeper in the grass even though the Blob is no longer a hole. Then while still deeper in the grass, keep walking right until you fall into the cave. Do that same trick again and walk right. You will notice that you are nowhere, that is good. You can you this glitch to pass all of the pointless parts until you see the boiling pot at the end.
On the first screen of the Blob's Planet, run and toss a jellybean at the left side of the screen. If you do it just right, the screen will flash for a moment and show the final boss room. Now, all enemies on Blobolonia will be gone for good.